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Arcade · Hack and slash/Beat 'em up · Indie

S.E.M.I.: Side Effects May Include...

About

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.

Developer
Two Horn Unicorn
Publisher
Two Horn Unicorn
Genres
Arcade, Hack and slash/Beat 'em up, Indie
Platforms

Ways to play

Co-operativeMultiplayerSingle player

Release information

PlatformRegionDate
worldwideNov 20, 2025
worldwideJan 23, 2026